**Study Overview:** 500 teachers from 25 schools implemented the Six-Pack Model over 6 months. Biomarkers were measured at baseline, 3 months, and 6 months. **Key Findings:** **Cellular Senescence Markers:** - p16 expression decreased by 34% (p < 0.001) - SA-β-gal activity reduced by 28% (p < 0.001) - Telomere length stabilized in 67% of participants **Stress Hormones:** - Morning cortisol levels normalized in 72% of participants - Cortisol awakening response improved by 41% - Chronic stress indicators decreased by 53% **Inflammation:** - CRP levels dropped by 45% on average - IL-6 concentrations reduced by 38% - Systemic inflammation reversed in 64% of participants **Correlation with Outcomes:** - Teachers with greatest biomarker improvements showed 2.3x higher retention rates - Student achievement gains correlated (r=0.67) with teacher biomarker recovery - Absenteeism decreased by 58% in teachers with normalized stress hormones **Conclusion:** Biomarker data provides objective evidence that the Six-Pack Model reverses teacher burnout at the cellular level, with measurable impacts on retention and student outcomes.